Greater Oklahoma City is in the geographic center of North America equidistant from the east and west coasts and major trade partners of Canada and Mexico. The ten county region is at the crossroads of the U.S., sitting at the heart of three major national highways on the NAFTA corridor.
There's a reason Greater Oklahoma City is such a great place for business: Location. The ten county region is positioned within a day's drive of the rapidly-growing south-central region (OK, TX, AR, LA) projected to grow more than 44% during the next 25 years.
Explore the counties and cities of Greater Oklahoma City including major employers and higher education. The ten county region boasts an average commute time of 20 minutes and a skilled workforce over half a million strong.
Noting low costs of living and good jobs, Forbes named Oklahoma City America's Most Affordable City.
At the height of the Great Recession, Forbes.com said Oklahoma City was the most recession-proof city in the country. Two and a half years later, the magazine has given the city another top ranking.
Noting low costs of living and good jobs, Forbes named Oklahoma City as America's Most Affordable City.
The magazine also noted Oklahoma City's friendly residents and an unemployment rate well below the national average, 6.3 percent compared to 9.5 percent.
"We searched for cities that had a balance of cheap living and economic prosperity - places with solid job markets, but where costs aren't prohibitive," magazine editors said. "In these cities, costs have stayed down, but residents have held onto steady incomes and decent jobs, making them a true bargain."
Forbes looked at all metropolitan statistical areas with populations of at least 100,000. They were ranked on the cost of a basket of goods and services, including groceries, health care and transportation, as of the second quarter of 2010.
The magazine also measured the monthly cost of housing as a percentage of household income.
The average sale price of an Oklahoma City-area home in September was $158,755, up 6.7 percent from September 2009, and the median price was $135,000, up 4.8 percent, according to the Oklahoma City Metro Association of Realtors.
The next four spots on the Forbes list went to Pittsburgh; Buffalo, N.Y.; Rochester, N.Y.; and Nashville, Tenn. The top 10 also includes three Texas cities: San Antonio, Houston and Austin, along with Louisville, Ky., and Birmingham, Ala.
"State capitals and university towns have vibrancy because of their job base, the stability of jobs and cultural diversification," said James Gaines, a research economist at the Real Estate Center at Texas A&M University.
Continuing praise
The ranking was the latest in a string of kudos for Oklahoma City. In October, Oklahoma City was named a Top 25 Performing City by the Milken Institute, No. 7 Best City for Income Growth by Portfolio.com, a Top 5 Fastest Growing City by Forbes and a Top 10 State for Doing Business by Area Development Magazine.
"In times like these, value is key to everything we do as a chamber," said Roy Williams, president and CEO of the Greater Oklahoma City Chamber. "From attracting new business, retaining and fostering growth with our current companies to attracting conventions and visitors, the number one factor on everyone's mind is value. Affordability isn't always about being the cheapest, it is also about the quality you get for your dollar."
The Boeing Co. recently announced plans to move 550 high-paying engineering jobs here. The company cited low costs of living and doing business and economic development incentives in the decision to move the jobs from Long Beach, Calif.
ATLANTA - The fertile mind of University of Oklahoma scientist Dr. Paul DeAngelis has yielded a sugar-based compound that is the basis of a fourth life sciences company.
Austin, Texas-based Emergent Technologies Inc. presented the technology of Caisson Biotech LLC at this week's Biotechnology Industry Organization conference here. Caisson is a subsidiary of Heparinex LLC, the Oklahoma City-based company that makes a synthetic blood anticoagulant.
Caisson Biotech will be based in San Antonio, although the synthesizing capabilities and manufacturing will remain in Oklahoma, said DeAngelis, Caisson's chief scientist.
Heparinex, Hyalose and Choncept all are Oklahoma City-based companies launched out of DeAngelis' research into sugar-based molecules at the OU Health Sciences Center.
Caisson Biotech will commercialize a patent-pending therapeutic delivery system called HEPylation, using a synthetic polymer similar to heparin.
Heparin was developed for use as an anticoagulation drug by DeAngelis, said John Hoopingarner, Emergent's executive vice president and chief development officer and president of Caisson Biotech.
Emergent is a life sciences technologies investment and management company with a portfolio that includes four Oklahoma City-based companies, three of which emerged from DeAngelis' research.
What are the uses?A brainstorming session for new uses of the heparosan polymer that is the "backbone" of the commonly used anticoagulant heparin led to the creation of Caisson Biotech in February, DeAngelis said.
"We were thinking of some other applications we could use it for - in this case, drug delivery," DeAngelis said. "All the cylinders hit with this. It has many good features."
The heparosan polymer provides protection against adverse reactions to the drug it helps deliver to the body, as well as provides a longer-lasting effect because it is not eliminated from the body as quickly as other delivery platforms.
"You don't make antibodies against it, and you don't have your protein enzymes dissolve it," DeAngelis said.
In his presentation to a BIO audience on Tuesday, Hoopingarner described the HEPylation process as a drug delivery platform biologically superior to the current industry standard polymer, called polyethylene glycol, or PEG.