OMRF research on skeletal diseases, blood vessels funded by NIH

Published: Wednesday, September 18, 2019 By: Dale Denwalt Source: NewsOK

The National Institutes of Health has awarded $3.6 million to researchers at Oklahoma Medical Research Foundation.

Lorin Olson, Ph.D., will receive $1.9 million over the next five years for his study into mutations that cause skeletal growth defects.

Another $1.75 million will go to Ray Rezaie, Ph.D., who studies the mechanisms that help maintain healthy blood vessels.

Olson will examine cellular mutations in two extraordinarily rare skeletal conditions, Penttinen syndrome and Kosaki overgrowth syndrome. Both diseases have fewer than 10 known cases globally. Although the mutations are different in each disease, both can be traced to one specific gene called PDGF receptor beta.

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